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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
12.73
Human Site:
S538
Identified Species:
20
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S538
P
F
P
E
G
T
A
S
N
V
T
V
M
P
P
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S538
P
F
P
E
G
T
A
S
N
V
T
V
M
P
P
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
P290
F
R
P
D
C
P
V
P
S
R
T
N
S
F
N
Dog
Lupus familis
XP_534537
1097
121903
Y525
L
R
C
P
P
P
P
Y
P
K
H
L
L
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S537
P
F
S
E
G
T
A
S
S
V
P
V
I
P
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
P529
P
F
S
E
G
P
A
P
N
V
S
V
M
S
P
Chicken
Gallus gallus
XP_419666
1136
127431
T544
P
F
S
E
G
P
S
T
N
M
A
V
M
P
P
Frog
Xenopus laevis
NP_001087838
1118
125984
Q533
V
P
H
N
T
S
T
Q
H
V
E
A
P
N
Y
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
A524
C
S
K
E
G
D
A
A
D
N
E
N
D
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
E527
Q
R
E
R
D
Q
R
E
R
E
R
D
Q
Q
K
Honey Bee
Apis mellifera
XP_395146
1137
124999
E574
D
G
C
Q
H
P
T
E
A
P
P
L
P
P
V
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
K614
V
R
S
T
T
V
A
K
P
V
L
Q
K
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
Q237
Q
Q
Q
H
M
Q
I
Q
Q
Q
Q
Q
Q
Q
Q
Red Bread Mold
Neurospora crassa
P38679
598
67999
I79
H
Q
F
A
H
Q
N
I
G
S
A
G
R
A
S
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
13.3
0
N.A.
73.3
N.A.
N.A.
66.6
60
6.6
20
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
100
26.6
13.3
N.A.
86.6
N.A.
N.A.
73.3
80
20
33.3
N.A.
0
20
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
40
7
7
0
14
7
0
14
0
% A
% Cys:
7
0
14
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
7
7
0
0
7
0
0
7
7
0
7
% D
% Glu:
0
0
7
40
0
0
0
14
0
7
14
0
0
0
0
% E
% Phe:
7
34
7
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
7
0
0
40
0
0
0
7
0
0
7
0
0
0
% G
% His:
7
0
7
7
14
0
0
0
7
0
7
0
0
0
7
% H
% Ile:
0
0
0
0
0
0
7
7
0
0
0
0
7
0
0
% I
% Lys:
0
0
7
0
0
0
0
7
0
7
0
0
7
0
7
% K
% Leu:
7
0
0
0
0
0
0
0
0
0
7
14
7
7
0
% L
% Met:
0
0
0
0
7
0
0
0
0
7
0
0
27
0
0
% M
% Asn:
0
0
0
7
0
0
7
0
27
7
0
14
0
7
7
% N
% Pro:
34
7
20
7
7
34
7
14
14
7
14
0
14
34
34
% P
% Gln:
14
14
7
7
0
20
0
14
7
7
7
14
14
14
7
% Q
% Arg:
0
27
0
7
0
0
7
0
7
7
7
0
7
0
7
% R
% Ser:
0
7
27
0
0
7
7
20
14
7
7
0
7
7
7
% S
% Thr:
0
0
0
7
14
20
14
7
0
0
20
0
0
7
0
% T
% Val:
14
0
0
0
0
7
7
0
0
40
0
34
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _